02071nas a2200253   4500008004100000245009000041210006900131260003800200300001600238490000700254520127800261653001201539100001701551700001501568700001201583700001601595700002001611700001501631700001701646700001501663700001501678700001601693856010801709       2007                        eng d00aThe Effect of Visual Experience on the Development of Functional Architecture in hMT+0 aEffect of Visual Experience on the Development of Functional Arc  bOxford University PresscMarch 19  a2933 - 29390 v173 a<p>We investigated whether the visual hMT+ cortex plays a role in supramodal representation of sensory flow, not mediated by visual mental imagery. We used functional magnetic resonance imaging to measure neural activity in sighted and congenitally blind individuals during passive perception of optic and tactile flows. Visual motion-responsive cortex, including hMT+, was identified in the lateral occipital and inferior temporal cortices of the sighted subjects by response to optic flow. Tactile flow perception in sighted subjects activated the more anterior part of these cortical regions but deactivated the more posterior part. By contrast, perception of tactile flow in blind subjects activated the full extent, including the more posterior part. These results demonstrate that activation of hMT+ and surrounding cortex by tactile flow is not mediated by visual mental imagery and that the functional organization of hMT+ can develop to subserve tactile flow perception in the absence of any visual experience. Moreover, visual experience leads to a segregation of the motion-responsive occipitotemporal cortex into an anterior subregion involved in the representation of both optic and tactile flows and a posterior subregion that processes optic flow only.</p>
10aHaptics1 aRicciardi, E1 aVanello, N1 aSani, L1 aGentili, C.1 aScilingo, E. P.1 aLandini, L1 aGuazzelli, M1 aBicchi, A.1 aHaxby, J V1 aPietrini, P  uhttp://95.110.227.16/publications/effect-visual-experience-development-functional-architecture-hmt.html